A three-tier herbal system designed for people living with multiple sclerosis who want research-backed botanical support alongside conventional treatment. 20 active compounds working across three interconnected pathways.
Consult your neurologist or healthcare provider before starting any herbal supplement related to your MS condition, especially if you are taking disease-modifying therapies or other prescribed medications. This protocol is not a substitute for medical treatment. N&O LLC is not responsible for any side effects or for interference with prescribed medications. Individual responses vary; if you experience any adverse effect, stop use and contact your provider.
The MS Complete Protocol™ supports three systems that matter to people living with MS — cellular energy, myelin health, and nerve health. Each tier builds on the one before it.
Support cellular energy production at the mitochondrial level. The foundation everything else depends on.
Support myelin health and a healthy inflammatory response with compounds studied for nerve support.
Support healthy immune balance and antioxidant defense for the nervous system.
Follow this daily schedule. All three products are taken at different times to optimize absorption and maintain steady compound levels throughout the day.
Take 3 capsules with breakfast. Include a source of fat (eggs, avocado, butter, nuts) for optimal absorption of fat-soluble compounds including Boswellia, D3, and K2.
Take 2 capsules between 3:00 and 5:00 PM with a small snack containing fat. This timing maintains steady compound levels through the evening and overnight hours.
NMN with TMG methylation support, KSM-66® ashwagandha, phosphatidylserine, saffron, and PQQ — every ingredient sleep-safe or sleep-positive. Taking at bedtime with a little fat aligns mitochondrial support with the body's natural overnight recovery cycles.
Complete transparency — no proprietary blends, no hidden doses. Every compound is selected for a specific mechanism described in the published research.
Supports myelin health, a healthy inflammatory response, and nerve function. Seven compounds working synergistically for myelin support.
2,260mg total · 8 Compounds
Supports nerve health, immune balance, and antioxidant defense. Five compounds selected to support the nervous system through the afternoon and evening.
1,712mg total · 6 Compounds
Supports cellular energy production, NAD+ levels, healthy cortisol balance, and mitochondrial biogenesis overnight. Six sleep-safe compounds at maximum studied doses.
2,748mg total · 6 Compounds
The MS Complete Protocol™ was formulated with drug interaction profiles in mind. After replacing Lion's Mane with Gotu Kola to eliminate immune-stimulating beta-glucan concerns, the protocol carries zero CAUTION flags across all major MS disease-modifying therapy (DMT) classes.
Avonex®, Betaseron®, Rebif®, Plegridy® — no herb-drug interactions identified.
Ocrevus®, Kesimpta®, Rituxan® — no herb-drug interactions identified.
Tecfidera®, Vumerity®, Bafiertam® — no herb-drug interactions identified.
Gilenya®, Mayzent®, Zeposia®, Ponvory® — moderate flag only for CYP450 metabolic overlap. Discuss with your neurologist.
Tysabri® — no herb-drug interactions identified.
Aubagio® — no herb-drug interactions identified.
This compatibility assessment is based on published pharmacological data and is provided for informational purposes only. Always consult your neurologist or healthcare provider before adding any supplement to your MS treatment regimen. N&O LLC is not responsible for side effects or interference with prescribed medications. See our Protocol Guide for the complete herb-drug interaction matrix and 32 peer-reviewed references.
The MS Complete Protocol™ is backed by extensive published research. Download our clinical documents for the complete picture.
Complete formula with ingredient rationale and mechanism of action
Herb-drug interaction matrix + 32 peer-reviewed references
Detailed Myelin Shield™ PROTECT AM & PROTECT PM breakdown
Full interaction profiles across all MS medication classes
About the Formulator. Dr. Paulette Y. Jones holds a Doctor of Nursing Practice (DNP) with a specialization in Nursing Leadership (DNP-L) and is a Registered Nurse (RN). Dr. Jones is not a medical doctor (MD or DO), is not a nurse practitioner (NP or APRN), and is not a licensed independent prescriber. She does not hold prescriptive authority and does not practice medicine. In connection with N&O LLC, Dr. Jones acts solely as a product formulator, researcher, and wellness entrepreneur. Nothing on this website, on N&O LLC packaging, or in any communication from N&O LLC constitutes medical advice, diagnosis, or treatment, and no provider–patient relationship is created by purchasing or using any N&O LLC product.
Consult Your Provider First. Before taking any N&O LLC supplement, powder, capsule, or tea, consult your own primary care provider, prescribing clinician, or pharmacist — especially if you are pregnant, nursing, or trying to conceive; under 18; taking any prescription medication (including blood thinners, diabetes, blood pressure or heart medication, antidepressants or other psychiatric medication, thyroid or seizure medication, immunosuppressants, or disease-modifying therapies); living with a diagnosed medical condition; or scheduled for surgery. Bring the full ingredient list to that conversation. Your provider, not N&O LLC, should decide whether a product is appropriate for you.
Regulatory Statement. *These statements have not been evaluated by the U.S. Food and Drug Administration. N&O LLC products are dietary supplements and are not intended to diagnose, treat, cure, or prevent any disease. Dietary supplements are not a substitute for prescribed medication, and no N&O LLC product should be used to replace, reduce, or discontinue any medication without the direction of the prescribing provider. Product and protocol names (including “Shield,” “Guardian,” “Protect,” and similar words) are brand names describing intended wellness support and do not represent claims of medical efficacy. Interaction information is compiled from published literature, is not exhaustive, and should be re-verified with a professional before being relied upon. If you experience an unexpected symptom, stop use and contact your provider.