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Hawthorn

I take a blood-pressure pill. Can I add hawthorn?

By Dr. Paulette Y. Jones, DNP-L, RN · N&O LLC

Hawthorn and Blood-Pressure Medication: A Nurse's Guide

Crataegus species

Hawthorn is the botanical I reach for first when someone asks about heart support, and it is one of the few herbs with decades of European clinical use behind it. It is also a herb that works in the same direction as several common medications, which is why the combination needs a provider's eyes on it.

What it is

Hawthorn is a thorny shrub whose leaves, flowers, and berries have been used for the heart in European tradition since at least the 1600s. The active compounds are flavonoids and oligomeric procyanidins. In studies they modestly dilate blood vessels, support the strength of the heart's contraction, and act as antioxidants. In Germany, standardized hawthorn extract is an approved remedy for mild heart complaints.

What the research has looked at

Doses used in research

Clinical trials generally used 160–1,800 mg per day of standardized leaf-and-flower extract, most often in the 500–900 mg range, for at least 6–8 weeks. Heart Guardian uses 500 mg of hawthorn extract.

Interactions and cautions

Hawthorn can add to the effect of blood-pressure medications and nitrates, and it may interact with digoxin and other heart medications. That does not mean it cannot be used — it means the dose of the medication may need attention and blood pressure should be monitored. Anyone with a diagnosed heart condition should use hawthorn only with their cardiologist's knowledge.

Drug / conditionSeverityWhyWhat to do
DigoxinMODERATEAdditive inotropic effect / may alter digoxin levelsMonitor; consult cardiologist
Beta-blockers, calcium channel blockers, nitrates, PDE-5 inhibitors (sildenafil)MODERATEAdditive vasodilation / hypotensionMonitor BP; caution with sildenafil
AntiarrhythmicsMODERATEAdditive effectsCardiologist approval
AnticoagulantsMINORMild antiplateletMonitor
Who should not take it without a provider's approval: Anyone on digoxin, nitrates, or blood-pressure medication without provider approval; diagnosed heart disease without cardiologist approval; pregnancy; two weeks before surgery.

Where we use it

Hawthorn extract 500 mg is the foundation of Heart Guardian, alongside hibiscus, olive leaf, garlic, artichoke leaf, and CoQ10 ubiquinol — a formula designed to support blood pressure and cholesterol already within the normal range.

Dr. Paulette Y. Jones holds a Doctor of Nursing Practice in Leadership (DNP-L) and is a Registered Nurse with nearly thirty years of clinical experience. She is the founder and formulator of N&O LLC. This article is for education only and is not medical advice. *These statements have not been evaluated by the Food and Drug Administration. N&O LLC products are not intended to diagnose, treat, cure, or prevent any disease. Always consult your healthcare provider before starting, stopping, or combining any supplement with a medication.

Selected peer-reviewed references

Peer-reviewed journal sources supporting this article, prioritizing systematic reviews, meta-analyses, and randomized trials from the past five years. Current as of September 2026.

About the Formulator. Dr. Paulette Y. Jones holds a Doctor of Nursing Practice (DNP) with a specialization in Nursing Leadership (DNP-L) and is a Registered Nurse (RN). Dr. Jones is not a medical doctor (MD or DO), is not a nurse practitioner (NP or APRN), and is not a licensed independent prescriber. She does not hold prescriptive authority and does not practice medicine. In connection with N&O LLC, Dr. Jones acts solely as a product formulator, researcher, and wellness entrepreneur. Nothing on this website, on N&O LLC packaging, or in any communication from N&O LLC constitutes medical advice, diagnosis, or treatment, and no provider–patient relationship is created by purchasing or using any N&O LLC product.

Consult Your Provider First. Before taking any N&O LLC supplement, powder, capsule, or tea, consult your own primary care provider, prescribing clinician, or pharmacist — especially if you are pregnant, nursing, or trying to conceive; under 18; taking any prescription medication (including blood thinners, diabetes, blood pressure or heart medication, antidepressants or other psychiatric medication, thyroid or seizure medication, immunosuppressants, or disease-modifying therapies); living with a diagnosed medical condition; or scheduled for surgery. Bring the full ingredient list to that conversation. Your provider, not N&O LLC, should decide whether a product is appropriate for you.

Regulatory Statement. *These statements have not been evaluated by the U.S. Food and Drug Administration. N&O LLC products are dietary supplements and are not intended to diagnose, treat, cure, or prevent any disease. Dietary supplements are not a substitute for prescribed medication, and no N&O LLC product should be used to replace, reduce, or discontinue any medication without the direction of the prescribing provider. Product and protocol names (including “Shield,” “Guardian,” “Protect,” and similar words) are brand names describing intended wellness support and do not represent claims of medical efficacy. Interaction information is compiled from published literature, is not exhaustive, and should be re-verified with a professional before being relied upon. If you experience an unexpected symptom, stop use and contact your provider.