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Signature Protocol

GLP-1 Weight Management Protocol

AM · Noon · PM Metabolic Support System

A research-based, three-product herbal protocol targeting the same GLP-1, fat-mobilization, and fat-oxidation pathways as prescription weight management medications — through 16 synergistic botanical compounds delivered across three daily phases.

3
Products
16
Active Compounds
AM/Noon/PM
Daily Protocol
3
Phases

How to Take the GLP-1 Protocol

Follow this daily schedule for optimal results. Consistency is key — take your formulas at the same times each day.

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Step 1 · First Thing in the Morning

Lemon-Chia Water

Start your day with warm water, one whole lemon squeezed in, and 1 teaspoon of chia seeds. Steep for 15 minutes, then drink. This stimulates gastric filling and bile production for natural appetite suppression before you eat anything. A whole fresh lemon is ideal, but 100% lemon juice is fine as a substitute.

Lemon-chia water in the morning only. In the afternoon before your Metabolic Boost PM, use plain chia water (no lemon).
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Step 2 · With Breakfast

Metabolic Core AM — 2 Capsules

Take 2 capsules of Metabolic Core AM with your breakfast meal. This is your primary metabolic activation — targeting GLP-1 pathways, fat mobilization, and fat oxidation through berberine, forskolin, L-carnitine, and 6 additional synergistic compounds.

2 capsules with breakfast. Size 000 capsules. Take with food to maximize absorption and minimize any GI sensitivity from berberine.
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Throughout the Day

Protein Shakes — 30g Each

Aim for 3 protein shakes throughout the day (morning, noon, and evening) at 30g protein each for a total of 90g daily. This preserves lean muscle mass during weight loss and supports satiety between meals. Supplement with small portions of lean meat and salad.

Important: If you have kidney disease or a history of renal impairment, consult your medical provider before increasing your protein intake. High protein consumption may not be appropriate for individuals with compromised kidney function.
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Step 4 · With Lunch (Phase 3 Only)

Metabolic Ignite — 1 Capsule

Once you've successfully completed Phases 1 and 2, you may advance to Phase 3 by adding Metabolic Ignite at lunch. This midday thermogenic formula activates brown adipose tissue during your most metabolically active hours and blocks starch absorption from the lunch meal through green tea EGCG, L-Carnitine, White Kidney Bean, Capsimax®, and Paradoxine®. Also available in a caffeine-free version.

1 capsule with lunch — must be taken WITH food (White Kidney Bean requires a starch substrate to work). Caffeine version must NOT be taken after 2 PM to prevent sleep disruption.
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Step 5 · 3:00 – 5:00 PM

Metabolic Boost PM — 1/4 Teaspoon

Start with your afternoon chia water (warm water and 1 teaspoon chia seeds — steeped 15 minutes; no lemon needed). Then take your Metabolic Boost PM between 3:00 and 5:00 PM with a small snack containing fat (yogurt, nuts, avocado). This sustains appetite control through the evening when cravings are strongest. Saffron, chromium, and adaptogenic herbs work together to modulate hunger signals and support metabolic function.

Step 1: Drink your afternoon chia water (no lemon).
Step 2: 1/4 teaspoon Metabolic Boost PM mixed into yogurt, a smoothie, or warm water. Always take with a small fat-containing snack for optimal absorption.

Natural Appetite Suppression Before You Take a Single Capsule

This simple daily ritual produces appetite suppression comparable to prescription GLP-1 medications through two mechanisms: gastric filling from chia seed expansion and bile stimulation from whole lemon.

1

Warm Water

Start with a glass of warm (not hot) water

2

Whole Lemon

Squeeze one whole fresh lemon into the water (100% lemon juice is fine too)

3

Chia Seeds

Add 1 teaspoon of chia seeds

4

Steep & Drink

Let it steep 15 minutes, then drink. Use in the morning only. In the afternoon, use plain chia water (no lemon) before your Metabolic Boost PM.

Three Formulas. One System.

Each product targets different metabolic pathways at different times of day. Customers start with Phase 1 (foundation dosing of Core + Boost), advance to Phase 2 (increased dosing) after Week 4, then advance to Phase 3 by adding Metabolic Ignite at lunch.

Metabolic Core AM

Morning · 2 Capsules · Size 000 · With Breakfast

Morning metabolic activation targeting GLP-1 signaling, fat mobilization, and fat oxidation pathways.

Phase 1 — Foundation (Weeks 1–4)

  • Berberine500mg
  • Cinnamon500mg
  • Fenugreek500mg
  • Turmeric500mg
  • EGCG (Matcha Green Tea)250mg
  • BioPerine®50mg

6 Core Compounds · GLP-1 Signaling & Appetite

Phase 2 — Advanced (After Week 4) · All Phase 1 ingredients plus:

  • Berberine (enteric-coated)300mg ↓ from 500mg
  • Gymnema Sylvestre (Gurmar/Sugar Destroyer)400mg NEW
  • ForsLean® Forskolin 20%250mg NEW
  • L-Carnitine Tartrate500mg NEW

+ 3 New Compounds · Fat Mobilization & Fat Oxidation

Metabolic Boost PM

3:00–5:00 PM · 1/4 Teaspoon · Powder or Capsule · With Fat

Afternoon craving control, mood support, and sustained metabolic function. Available as a powder or in capsule form.

1/4 teaspoon between 3:00–5:00 PM with a small fat-containing snack (yogurt, nuts, avocado). Mix into yogurt, smoothie, or warm water.

Phase 1 — Foundation (Weeks 1–4)

  • 10-in-1 Mushroom Blend500mg
  • Ashwagandha KSM-66300mg
  • Resveratrol200mg
  • Cayenne150mg
  • 5-HTP100mg
  • Saffron (Super Negin)30mg

6 Compounds · Satiety, Cortisol & Thermogenesis

Phase 2 — Advanced (After Week 4) · Increased metabolic drivers:

  • 10-in-1 Mushroom Blend500mg
  • Ashwagandha KSM-66600mg
  • Resveratrol400mg
  • Cayenne300mg
  • 5-HTP100mg
  • Saffron (Super Negin)30mg

3 Metabolic Drivers Increased · Neurochemical Doses Held Safe

Metabolic Ignite

Noon · 1 Capsule · Size 00 · With Lunch

Midday thermogenic activation. Ignites brown adipose tissue during peak metabolic hours and blocks starch absorption from the lunch meal.

Phase 3 — Advanced (After Phases 1 & 2 Complete)

  • Green Tea Extract (50% EGCG)300mg
  • L-Carnitine Tartrate (Carnipure®)500mg
  • White Kidney Bean (Phase 2®)500mg
  • Caffeine Anhydrous100mg
  • Capsimax® (Capsicum)50mg
  • Paradoxine® (Grains of Paradise)40mg
  • BioPerine®5mg

7 Compounds · Thermogenesis & Starch Blocking

Caffeine-Free version available for customers sensitive to stimulants or those who take it later in the day. Must always be taken WITH lunch — White Kidney Bean requires a starch substrate to block absorption.

Advancing to Phase 2: Customers must complete a minimum of 30 days on Phase 1 with good tolerance, demonstrate a weight loss plateau of 2+ weeks, complete serotonergic medication safety screening (critical for 5-HTP), and maintain adequate daily water intake (minimum 64 oz/day). Phase 2 is available as a premium subscription tier.

Advancing to Phase 3: After successfully completing Phases 1 and 2 with stable results, customers may add Metabolic Ignite at lunch for enhanced thermogenic and starch-blocking support. Screening for caffeine sensitivity, blood pressure, and heart conditions is required — a caffeine-free version is available. Always take Ignite WITH food.

You've Reached Your Goal Weight on Your GLP-1 Injection.
Now Maintain Your Progress — Naturally.

Prescription GLP-1 medications like semaglutide and tirzepatide are powerful tools. They work. But many patients reach their desired weight and face a difficult choice: stay on an expensive injection indefinitely, or stop and risk regaining everything they've lost.

There is a third option.

N&O LLC's GLP-1 Weight Management Protocol targets the same metabolic pathways through research-backed botanical compounds — offering a gentler, more affordable way to sustain your progress after you've done the hard work with your prescription. No abrupt stop. No shock to your system. Just a thoughtful transition from pharmaceutical support to herbal maintenance.

Herbs are for prevention and terrain support. Conventional medicine is for when it's medically necessary. They are not enemies — they are partners.

— Dr. Paulette Y. Jones, DNP

Same Pathways, Gentler Approach

Our protocol targets GLP-1 signaling, fat mobilization, fat oxidation, and thermogenesis through 16 botanical compounds — the same metabolic pathways addressed by prescription medications.

A Fraction of the Cost

Prescription GLP-1 injections can cost $300–$1,000+ per month. Our herbal protocol provides ongoing metabolic support at a price that doesn't force you to choose between your health and your budget.

Protect Your GI Health

Long-term use of prescription GLP-1 medications has been associated with serious gastrointestinal complications. A botanical approach supports your metabolism without those risks.

Where Do I Start?

Coming off a GLP-1 injection? Start with Phase 2 — the advanced formula. Your body is already accustomed to strong metabolic support from your prescription. Phase 2 provides the level of herbal support needed to maintain your progress and prevent rebound weight gain during the transition.

New to GLP-1 support? Start with Phase 1 — the foundation formula. This allows your body to adjust gradually, establishes your metabolic baseline, and assesses your tolerance before advancing.

Always consult your healthcare provider before discontinuing any prescription medication. N&O LLC's GLP-1 Protocol is not a replacement for prescribed medical treatment. It is a research-based herbal option for people who, with their provider's guidance, are choosing to transition to botanical metabolic support.

Ready to start the protocol?

Order the GLP-1 Weight Management Protocol as a bundle or subscribe for auto-ship savings.

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*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before starting any supplement regimen, especially if you are taking medications or have a medical condition.